Rotherham manager Ronnie Moore will hand a debut to his son, Ian Thomas-Moore, in the game.
The 34-year-old striker, who has signed an 18-month deal after an undisclosed fee was agreed with Tranmere for his services, will go straight into the starting line-up against County following the Millers dismal performance in losing 3-0 at Stevenage in midweek.
The experienced frontman is likely to partner Adam Le Fondre in attack despite the fact League Two’s leading goalscorer has failed to find the net in any of his last six games in all competitions.
However, midfielder Jason Taylor will sit out for the second time in a week as he continues his three-match suspension and defender Ryan Cresswell remains sidelined as he recovers from a broken collarbone.
Stockport have been handed a double boost ahead of the trip to Rotherham after signing defenders Daniel O’Donnell and Aaron Brown.
O’Donnell progressed through the ranks at Liverpool and played for Crewe before joining Shrewsbury last August.
However, his contract with the Shrews expired at the end of December and County have handed him a deal until the end of the season.
Brown joins from Leyton Orient on a one-month loan deal and he and O’Donnell will hope to plug County’s leaky defence.
Stockport have failed to keep a clean sheet in the last 12 games and have the unenviable record of 61 goals against in just 27 games.
Caretaker boss Peter Ward said: “Everyone can see where the problem lies.”