Low said: “Schweinsteiger probably won’t play on Sunday.
“The medical staff said he has to take a break for two or three days.
“He will stay with us and we will see what is possible. But it does not look like he can play.”
Schweinsteiger faces a race to be fit for United’s trip to Everton on October 17, with captain Wayne Rooney also missing England’s qualifying double-header due to injury.