Jean-Louis Akpa Akpro is available after signing a new one-year deal to stay at Shrewsbury on Thursday.
Junior Brown, Shaun Whalley, Abu Ogogo and Martin Woods are all set for their Shrewsbury debuts against Millwall after joining in the summer.
Left-back Mat Sadler could also mark the start of his second spell after returning to the club after leaving Rotherham.
James Wesolowski and Nathaniel Knight-Percival have returned to training after cruciate knee ligament injuries but are not ready for first-team action.
Millwall’s new signing Steve Morison is expected to spearhead the Londoners’ attack.
Morison completed his return to Millwall from Leeds earlier in the week and is likely to go straight into manager Neil Harris’ starting line-up. Fellow forward Aiden O’Brien is nursing an ankle injury and could miss out.
Midfielder Jimmy Abdou is struggling with a hamstring injury and will not be risked, while left-back Joe Martin remains doubtful after missing the final pre-season friendly against Portuguese side Tondela due to an ankle problem.
Long-term absentee Carlos Edwards (knee) returned to action in a recent behind-closed-doors friendly against AFC Wimbledon, but is not yet in contention.