Adams scored a headed goal playing for Oldham at Boundary Park back in 1993 to earn the Latics three points which proved valuable in avoiding relegation on goal difference.
The United side that day included a teenage Giggs and it is the Welshman who Adams will be pitting his wits against at Old Trafford as he tries to enjoy his first game in charge since taking over from the sacked David Moyes.
"I once went three days without watching it," said Adams of possibly the most important goal of his career.
"It was a big goal at the time. When you score against Man United, you never tend to forget it.
"It was a good day, a 1-0 win and a header. I was pleased with it. It was about three yards out. I'll take one of those on Saturday.
"These are three huge games for this football club and one thing we can guarantee is we'll be giving it everything we've got and be as best prepared as we possibly can.
"We're confident going into the game and we'll be confident going into the other two.
"If you're organised, you feel you're ready and you prepare the players in the right way, why not? We feel confident we can go and have a good go at it."
Adams has no idea what to expect from Giggs, although he admits to having some sympathy for what he is going through, having himself only replaced Chris Hughton a couple of weeks ago.
"It's a whirlwind for him now. He'll be doing a million and one things," Adams added. "What he'll want to do is get out there on the pitches, get his team sorted.
"He's been involved in winning things year in year out - you can't fail to be inspired by that sort of education.
"He's been doing his coaching badges, he's been learning from the best and he must have a vast amount of knowledge from what he's seen and what he's learned.
"He commands instant respect. It's probably the reason why he's been given the interim job - because the players know and respect him. He's got an opportunity now in these few games to go and have a crack at it."