The Jags striker was clean through five minutes after the break and looked odds-on to give Alan Archibald's men the lead and with it a chance to secure their first home league win of the season.
However, the Hibees captain stood his ground as Doolan bore down on him and made a crucial save, with the Maryhill men ultimately paying for their wastefulness - which is fast becoming a feature of their season - when midfielder Liam Craig scored a well-taken winner for the visitors.
Doolan, 26, told Press Association Sport: "I put my hands up. I was clean through and I've got to score.
"I'm big enough to take that on the chin.
"I had my mind made up from the minute I went through and then I changed it at the last minute.
"The goalie did well to stay up so long and he has made me change my mind.
"I have scored plenty of goals across the years, and along with that you have to miss some.
"If you are the one in there trying to take all the chances you are going to miss.
"But I will be in there to put the next one in."
Thistle passed up on the chance to leapfrog Pat Fenlon's side into the top half of the table but remain in eighth place with 10 points from nine games.
Doolan, who joined Thistle from Junior side Auchinleck Talbot in 2009 before a loan spell at Clyde, insists there is no need for anyone at the club to be downhearted about their start to the season in their return to the top flight.
"If someone had offered this start I'm sure we would have taken it," he said.
"Obviously here and there we could have picked up extra points to have us higher up the league but the reality is we are not and we have to deal with that and pick ourselves up.
"Nobody feels sorry for us and we don't feel sorry for ourselves so we will need to get on with it.
"I know we haven't taken the chances that we should have this season but once it all clicks together, more will fly in.
"And once we start picking up those points that we are throwing away we will be fine.
"If it would be worse if we were playing poorly, then it might be easier to point fingers at us.
"But we are playing well so we have to take the positives from every game and that's what we will do."