The 20-year-old has become one of the most sought-after talents in Italian football, with his considerable promise having been noted by clubs across the continent.
A number of assured displays in Serie A have helped to convince those suitors that the time may be right to make a move.
With the January transfer window open, an opportunity to talk terms has presented itself and Southampton may be tempted to try and add Sorensen to their defensive ranks.
"It is correct that Southampton are among the clubs who have contacted Bologna regarding an interest in Frederik," Sorensen's representative, Michal Bolvig, told Sporten.dk.
"He has now produced regularly on a high level in a good league and it is natural that there is interest for a young player like him.
"The Premier League is an exciting option for Frederik. But he is not in a hurry to interrupt the progress he is going through at Bologna right now."
Denmark U21 international Sorensen, who joined Bologna from Juventus in January 2012, admits to enjoying his football at present, but has refused to be drawn into a debate regarding his future.
He said: "I am now playing at the heart of the defence, where I am best and feel most comfortable.
"I value the praise I have had from my coach and the club's sporting director. I am also happy for the responsibility I have got, although I am just 20 years old.
"It was not the same at Juventus."