Suarez spearheaded Liverpool's title bid last season as they just missed out to Manchester City for English football's top prize.
The Uruguayan, who scored 31 goals last season and won the PFA Player and Football Writers' Association Footballer of the Year prizes, left Liverpool for Barcelona earlier this month for a fee in the region of £75million.
Liverpool have brought in five new faces in the shape of Rickie Lambert, Adam Lallana, Emre Can and Lazar Markovic this summer and Agger believes they can help fill the void left by Suarez's departure.
"I don't think the transfer of Suarez is that tough." Agger told Ritzau.
"There are some new (players) who will take over. As soon as big players leave, there will be new ones who will come and some other players will raise their game.
"Hopefully, there will be more additions who will bring some qualities."
Agger's own future at Liverpool has been the subject of speculation this summer with Barcelona thought to be keen on luring the central defender away from Anfield after eight years at the club.