Strathclyde Police said a man, 24, two 16-year-old boys and an 18-year-old woman were arrested in Glasgow on Wednesday following an investigation into an incident on December 18 last year.
It is said to have happened during a Scottish Third Division fixture when Rangers beat visitors Annan Athletic 3-0.
Eight other men, aged between 17 and 31, were arrested on the day of the disturbance. They were released pending a court hearing at a later date.
The four people arrested on Wednesday, by the football co-ordination unit for Scotland, have also been released on an undertaking and are due to appear at Glasgow Sheriff Court on March 22.
A police spokesman said the disturbance was "brought swiftly under control" by stewards.