Italy head coach Cesare Prandelli has taken a hardline approach to Daniele De Rossi's indiscipline by dropping the Roma midfielder from his squad to face France.
The 29-year-old was sent off for punching Lazio captain Stefano Mauri in Sunday's Roman derby, a game Lazio won 3-2, with Prandelli applying his strict code of ethics by omitting De Rossi from his 25-man selection.
Prandelli has confirmed he will not include players dismissed for violent conduct or dissent, so De Rossi's place has been taken by his Roma team-mate Alessandro Florenzi, who is named for the first time.
Newcastle defender Davide Santon returns to the national set-up for the first time since March 2011 as the Azzurri prepare to face Les Bleus in a friendly at the Stadio Ennio Tardini on Wednesday evening.
Cagliari defender Davide Astori last featured in August's friendly against England, while the inclusion of AC Milan's Stephan El Shaarawy - who now has two caps - would appear to signal the end of the striker's career with the Under-21s.
Squad: Buffon (Juventus), De Sanctis (Napoli), Sirigu (Paris St Germain), Viviano (Fiorentina); Astori (Cagliari), Balzaretti (Roma), Barzagli (Juventus), Bonucci (Juventus), Chiellini (Juventus), Criscito (Zenit St Petersburg), Maggio (Napoli), Santon (Newcastle); Candreva (Lazio), Diamanti (Bologna), Florenzi (Roma), Giaccherini (Juventus), Marchisio (Juventus), Montolivo, Pirlo (Juventus), Verratti (Paris St Germain); Balotelli (Manchester City), Destro (Roma), El Shaarawy, Giovinco (Juventus), Osvaldo (Roma).