Genoa have sacked Luigi Del Neri following Sunday's 2-0 home defeat to Catania.
Del Neri only replaced Luigi Del Canio at the Stadio Luigi Ferraris on October 24 but a run of just two wins from 13 games sees the club languishing in the Serie A relegation places.
A statement on Genoa's official website tonight read: "Genoa announce that it has dismissed coach Luigi Del Neri.
"The club wishes to thank Mr Del Neri, and his team of assistants, Francesco Conti, Maurizio D'Angelo and Luca Alimonta, for their efforts during this period."
The club have yet to name a replacement, but former coach Davide Ballardini has been linked with the post in the Italian media.