Roma coach Rudi Garcia has told his players to focus on themselves and not Serie A leaders Juventus when they tackle bottom side Catania on Sunday.
The Giallorossi are second in the standings and need to win at Catania and then have Atalanta beat Juventus in Turin on Monday to keep their faint title hopes alive.
Juventus are eight points clear with three games to go.
"We are not thinking of Juve but of ourselves," Garcia said in Gazzetta dello Sport. "We needed a win to maintain second place.
"Mathematically, the title race goes on.
"There are still a few games left, including our home game against Juve, and still many things to achieve."
Roma go into the encounter in Sicily on the back of nine straight wins, including last weekend's 2-0 triumph over AC Milan.
The capital city giants face a Catania side who are battling for Serie A survival.
Catania are five points adrift of Sassuolo, who hold the last position in the safety zone.
Juventus will take on Atalanta on Monday knowing that a victory will see them crowned Italian champions for a third straight season.
Antonio Conte's men will return to action in Turin after seeing their hopes of playing in the Europa League final ended on Thursday.
Juventus failed to overturn a 2-1 first-leg deficit as they were held to a goalless draw at home by 10-man Benfica.
Napoli will head into Tuesday's home game against Cagliari needing a point to guarantee a third-place finish and the last Champions League qualifying spot.
Rafael Benitez's team, who take on Fiorentina in the Coppa Italia final on Saturday in Rome, are eight points clear of the Florence outfit in Serie A.
Fiorentina host Sassuolo on Tuesday needing to claim a point to assure themselves of a top-six finish that would allow them to play in Europe next season.
Fiorentina presently stand fourth, four points above nearest rivals Inter Milan.
Inter and AC Milan, who have had disappointing seasons, square off at the San Siro. Milan are 10th in the standings, six points adrift of Inter.
The battle to finish sixth, which will determine the last European qualifying spot, could hardly be any tighter.
Torino are sixth, level on 52 points with Lazio and Hellas Verona, who take on each other on Monday at the Stadio Olimpico.
The Turin outfit, who travel to Verona to face relegation-threatened Chievo, have won four of their last five league games.
Parma could get back in contention for European football next season if they beat Sampdoria at home on Sunday.
The Gialloblu have lost their last two league games and lie one point behind Torino.
Livorno have collected one point in their last seven encounters and are 19th, three points adrift of safety.
They face Udinese on Sunday at the Friuli Stadium.
Bologna, who are third bottom but level on 28 points with Sassuolo, visit Genoa.