After struggling with injuries since arriving from Bologna in the summer, Ramirez - who is Southampton's record signing - has impressed massively in recent weeks.
Speaking to Tuttomercatoweb, he admits he would contemplate a move back to Serie A but he insists that he is very happy in the Premier League.
"In Bologna I was fine, but now I think about Southampton," he said.
"Coming back to Italy? In England I discovered a fantastic football. But in life never say never, in Italy, as well as in England, there are many important teams."
Reports in Italy have linked him with Fiorentina and he admits he has been impressed by them under coach Vincenzo Montella.
"Me to Fiorentina? It would be nice, they are playing very well and I like coach (Vincenzo) Montella. In every game the team are having fun, they have great quality. Why not? I'd come back in Italy, I like it and I was fine there."