Spurs produced a superb performance to win 3-0 at White Hart Lane last week and travel to Italy for Thursday's return game in a strong position to go through to the quarter-finals.
Goalkeeper Friedel is focused on finishing the job and believes Tottenham should try and net an away goal which would leave Inter needing to score five times.
He said: "They are still in the match at 3-0, but we'll go out there with the attitude to score. And if we get that decisive away goal it will be a mountain to climb for them.
"Away goals are so important and getting a clean sheet is vitally important - as was the third goal before going to the San Siro.
"Before the game we would have taken 3-0."
Dawson is also confident that Tottenham can knock out Inter, even though they will be without the suspended Gareth Bale, but he does expect a response from the Serie A side.
"We all know how tough it is in the San Siro and one thing is for sure, they won't lie down," Dawson told the club's official website.
"There is a lot of pride at stake and I'm sure they will be hurting after losing 3-0 like they did at the Lane. We have to be ready for that.
"We're in a great position, don't get me wrong and we now have to go there, do a professional job and if we do that, we'll be okay. It won't be a walk in the park though, that's for sure."