The 24-year-old Corinthians star has been linked with a move to Spurs for several months and it appears he is now on the verge of completing a £17million move to London.
Paulinho, who has 17 international caps to his name and impressed throughout Brazil's recent Confederations Cup success, will become Andre Villas-Boas' first summer recruit as he looks to reshape his squad ahead of a push for a top-four place in the Barclays Premier League next season.
The player revealed during the tournament in his native country that a bid from Spurs to seal his signature had been lodged and that north London was his most likely destination.
Inter Milan and Real Madrid were also believed to be interested in a move for the former Bragantino midfielder, who scored twice during the Confederations Cup, following on from his equalising goal in Brazil's 2-2 draw with England last month.
If the medical goes without a hitch, Paulinho could be announced as a Tottenham player later on Friday.