West Brom have sacked Nicolas Anelka citing "gross misconduct" after the striker claimed on Twitter he had quit the club.
Mauricio Pochettino expects to be at Southampton next season and is looking forward to working with chairman Ralph Krueger.
Guardiola won two UEFA Champions League trophies as Barcelona coach but quit the Catalan club at the end of last season and has since been heavily linked with a switch to either Manchester City or Chelsea.
Asked if he had ever known a situation where a manager was so in-demand, Ferguson told Yahoo Sport: "That is difficult to say.
"I spoke to Pep a while ago and he said he has no interest in getting back into management at the moment.
"His record is fantastic. The trophies he won at Barcelona were quite exceptional and that is his CV - he wins trophies.
"Barcelona have always had that style and played attractive football. He increased that by putting a new work ethic into the players.
"They work extremely hard to get the ball back and if you combine that with their possession it makes a fantastic team."
Reports in Spain have suggested that Barca have contacted Guardiola about taking the reins back at Camp Nou for the rest of the season after it was confirmed that Tito Vilanova was again fighting cancer, but the Catalan club have denied these claims.