Karl Darlow is hoping to repay the support he has received since agreeing a move away from Nottingham Forest.
Northampton boss Aidy Boothroyd has left the club less than an hour after the final whistle of their 4-1 home defeat to Wycombe.
The former Watford boss had been in charge of the Cobblers since November 2011 and his struggling side had picked up two wins and two draws from their last five games heading into the clash with the Chairboys.
But Wycombe's comprehensive victory at Sixfields was to be Boothroyd's last in charge with the club's Twitter account announcing his departure at 5:39pm.
"The decision was made by Chairman David Cardoza after Saturday's loss to Wycombe Wanderers," a brief statement added.
"The club will make no further comment at this time, but will provide a further update on Monday."