Danny Welbeck (knee) is almost certainly out but could return the following week against former club Manchester United.
Mikel Arteta (ankle), Alex Oxlade-Chamberlain (groin) and Mathieu Debuchy (hamstring) remain absent, along with Abou Diaby (knee).
Swansea striker Bafetimbi Gomis is set to be thrust back into action at Arsenal on Monday night with loan signing Nelson Oliveira unlikely to play again this season.
Gomis has missed the last three games with a hamstring injury but has been back in training this week and his return could not be more timely with Oliveira having picked up an ankle injury against Stoke last weekend.
Spanish defender Jordi Amat (broken metatarsal) has joined Oliveira, Kyle Naughton, Tom Carroll and Wayne Routledge on the sidelines but full-backs Jazz Richards and Dwight Tiendalli are available following respective loan spells at Fulham and Middlesbrough.