Tom Aldred has torn his hamstring and is expected to miss the rest of the season, with the former Accrington defender booked in for a scan this week to determine the full extent of the damage.
Bournemouth loanee Miles Addison cannot return to the midfield either after receiving a blow to his knee which is likely to keep him out of the Seasiders’ next two fixtures.
Jamie O’Hara (ankle) returned to the team against Bolton but neither Henry Cameron (ankle) or Mark Waddington (foot) will play again this season.
Reading can welcome back midfielder Danny Williams after suspension.
The USA international missed Saturday’s 1-1 draw with Cardiff due to a one-match ban after he was sent off against Charlton a week earlier.
Nathaniel Chalobah and Simon Cox are battling to shake off the knocks which kept them sidelined at the weekend, while Jure Travner (groin) and Anton Ferdinand (calf) are still sidelined.
Kwesi Appiah is pushing to make his full debut having come on as a substitute against Cardiff following his loan switch from Crystal Palace.