Non-league sides Sutton United and Lincoln will both have home advantage in the FA Cup fourth round provided they win their third-round replays against Wimbledon and Ipswich respectively.
Sutton will welcome Cambridge or Leeds to Gander Green Lane if they see off the Dons at the second attempt, while Lincoln’s reward would be a home clash with Championship promotion chasers Brighton.
Chelsea will face Brentford in a west-London derby at Stamford Bridge, Manchester United welcome Wigan to Old Trafford and Manchester City travel to face either Crystal Palace or Bolton.
The winners of the replay between Plymouth and Liverpool will face Wolves, who pulled off one of the biggest shocks in round three with their win at Stoke.
Tottenham Hotspur v Wycombe Wanderers
Derby County v Leicester City
Oxford United v Newcastle United or Birmingham City
AFC Wimbledon or Sutton United v Cambridge United or Leeds United
Plymouth Argyle or Liverpool v Wolverhampton Wanderers
Southampton or Norwich City v Arsenal
Lincoln or Ipswich v Brighton
Chelsea v Brentford
Manchester United v Wigan Athletic
Millwall v Watford
Rochdale v Huddersfield Town
Burnley or Sunderland v Fleetwood Town or Bristol City
Blackburn Rovers v Barnsley or Blackpool
Fulham v Hull City
Middlesbrough v Accrington Stanley
Crystal Palace or Bolton v Manchester City