Hartlepool first-team coach Mick Wadsworth could name an unchanged side.
Wadsworth made two attacking changes against high-flying Charlton in midweek, with James Brown partnering on-loan forward Ryan Donaldson, and they impressed in the 2-1 victory.
However, Brown has struggled with knee problems throughout this season and his fitness will be assessed.
Colin Larkin, Leon McSweeney and utility-man Ritchie Humphreys will press for starting places after appearing as substitutes in the last two matches.
Steve Haslam is set to retain his place in the starting line-up as he continues to fill in at right-back for Neil Austin, who will miss his fourth successive game with a calf injury and is expected to be out for another two weeks.
Gary MacKenzie returns to the MK Dons defence.
The centre-half has missed the last two games through suspension but will come back into the starting XI in place of youngster Tom Flanagan.
Manager Karl Robinson, though, will make a late decision on the health of Danny Woodards and Jabo Ibehre.
Right-back Woodards missed the home defeat to Leyton Orient in midweek through illness, while striker Ibehre had to come off at half-time after scoring due to the same ailment.
The latter is hopeful of keeping his place but Robinson will monitor the pair before kick-off.
Fellow striker Sam Baldock is about 10 days away from a return following his latest hamstring injury and on-loan QPR frontman Angelo Balanta remains sidelined with his ankle problem.