Spurs head to Anfield for the first meeting between the sides since Liverpool beat Mauricio Pochettino’s side 2-0 in the Champions League final in June.
Liverpool go into the game three points clear at the top of the Premier League, while Spurs are 10th after a stuttering start to the campaign.
Van Dijk came out on top in their battle in Madrid but Kane is looking forward to the challenge and believes they can end Liverpool’s unbeaten run.
“Van Dijk is a great defender, but he’s not invincible and Liverpool are not invincible,” Kane told Sky Sports.
“We just have to concentrate on ourselves. Any team can be beaten on any day and we just have to try to make sure we do that at Anfield.
“As a striker, it’s not just one-v-one on the pitch, there’s a lot that goes into it. Van Dijk is an amazing defender and he has had a fantastic couple of years at Liverpool.
“So, from my point of view, it’s just about playing my game and making my movements, making my runs and trying to get on the scoresheet, trying to get assists.
“At the end of the day, it’s a team game, so we all have to be on it with each other and that’s the main aim.”
“You want to win, you want to come out on top and they came out on top in May, or June, whenever it was. I’ve tried to forget it.”