Both Philippe Coutinho and top scorer Mohamed Salah (groin) will miss the visit of Everton but the match could see a debut for £75million signing Virgil van Dijk.
The Holland international completed his move from Southampton on January 1 but Klopp is in no rush to send out the world’s most expensive defender.
“Mo and Phil are not available so it is not possible. With Virgil it is different, he is obviously healthy and I have to make a decision for this game,” said Klopp.
“I can imagine everyone is desperate to see him on the pitch but from our point of view there is no rush and it is much more important how many good games he can play for us.”
Loris Karius will start in goal with Simon Mignolet given the weekend off as third-choice Danny Ward will be on the bench.
The Wales international spent a successful season on loan at Huddersfield last year but has been restricted to one appearance in the Carabao Cup defeat at Leicester back in September.
That does not mean he – or any of his under-used team-mates – are primed for loans this month.
“Loris will play. I am pretty sure Wardy is sub, which means Simon has a little break,” said Klopp.
“Danny is a young, very skilled goalkeeper with a lot of potential which means space for improvement and we are quite desperate to build on that together with him.
“There is enough to do for all of the boys so there is no rush in that and we cannot help other clubs before we help ourselves.”