The Dutch winger suffered a sprained ankle during Saturday’s 1-1 draw at Burnley and head coach Mourinho believes the injury is bad enough to keep him out for the rest of the campaign.
It is a crushing blow for Mourinho and Spurs on the eve of their Champions League last-16 second leg with RB Leipzig, where they have to overturn a 1-0 deficit in Germany.
Bergwijn joins Harry Kane and Son Heung-min in the treatment room and Tottenham’s attacking options look bare for a game in which they must score two goals to progress in normal time.
“Steven, I don’t expect him to play this season,” Mourinho said. “Can I believe it? Yes, I can.
“I have never known it like this, especially speaking about traumatic injuries. Only Harry Kane’s injury was not a traumatic injury but a typical injury of the December period in the Premier League.
“Hugo Lloris, (Moussa) Sissoko, Sonny, Steven Bergwijn are all traumatic and never for a couple of weeks. That’s what it is.
“We were psychologically more down with the other injures.
“This one, from three, four or five to six or seven is the same. No problem.”