Both Vertonghen and Lamela are out for Spurs’ clash against Sheffield United this weekend with hmastring injuries.
And Pochettino revealed he had a discussion with Everton boss Marco Silva about injuries and how important it is to move on and focus on the players that are available for selection.
He said: “We were talking about Andre [Gomes], with Marco Silva, it is trying to help them to be in the best form and then give the opportunity to play and perform.
“The problem in the competition in the high level, you don’t have time to miss people.
“It is like now with [Erik] Lamela, or [Jan] Vertonghen, how you sit in the chair and cry because you miss someone. You miss the person, the professional, but the competition does not allow you to cry. You have to move on quick. It is a bit cruel, but you have to move on and try to win the next game.
“If you ask me like an MP, not as a coach, you miss the person when they are not involved, or close to you. Everyone provides different energy, but you cannot be affected. It is so important.”