Portsmouth skipper Liam Lawrence hopes to be fit.
The winger sustained a knee injury during last Saturday’s 2-0 defeat at Reading but a scan has shown he did not suffer any ligament damage.
Boss Steve Cotterill will be forced to break up the defence which has kept eight clean sheets in 10 matches as Ricardo Rocha serves a one-match ban following his red card at the Madejski Stadium.
Aaron Mokoena, Carl Dickinson or Ibrahima Sonko will step into the back four.
David Nugent will start against his former club while fellow striker Danny Webber will be on the bench after his late cameo last week – his first appearance since suffering a cruciate injury over a year ago.
On-loan defender Ricardo Gardner has returned to Bolton ahead of Preston’s trip to the South Coast.
The Jamaica international jarred a knee in last weekend’s win over Swansea and subsequently missed Tuesday’s 2-1 defeat at Reading.
However, his loan expired after the match at the Madejski Stadium and he has headed back to the Reebok Stadium to try and force his way back into Owen Coyle’s plans.
North End boss Phil Brown is already without Conor McLaughlin, who is out for the season with a long-term ankle injury, and David Gray is still on crutches after taking a knock to his shin at Norwich last month.
Defender Leon Cort and strikers Chris Brown and Leon Clarke are edging closer to full fitness again and may come into contention.