Preston’s injured strike duo Iain Hume and Neil Mellor are making good progress in their efforts to return, but the clash could come too soon.
Hume and Mellor, suffering from knee and ankle problems respectively, have been absent for the Lilywhites, who have not won in their last five matches, in recent weeks.
There is an outside chance the duo could feature against the Cherries, although next week’s trip to Charlton could prove a more realistic return game.
Barry Nicholson is pushing for a starting berth after coming off the bench for the final 10 minutes of Tuesday’s 3-3 draw with Oldham.
Darel Russell impressed in making his first start of the season against the Latics and should keep his place in the XI.
Striker Jamie Proctor will miss out after it was this week announced he will undergo a hernia operation on November 1.
Bournemouth’s new signing Steve Cook is likely to be handed his debut in the away tie.
The centre-back joined the Cherries on an emergency loan deal from Brighton on Thursday and is set to replace the suspended Stephane Zubar at the heart of defence.
Zubar picked up a one-match ban after being shown his fifth yellow card of the season during the 1-1 draw at Colchester on Tuesday.
Meanwhile, striker Charlie Sheringham will sit out the trip to Deepdale because of suspension. The son of former England star Teddy arrived at the Seward Stadium last week from Dartford and made his debut in Essex. However, Sheringham collected five yellow cards for his previous club earlier in the campaign, and will serve a one-game ban this weekend.
Manager Lee Bradbury will be without Joe Partington, who was withdrawn at half-time at Colchester due to an impact injury on his ankle. The midfielder underwent a scan following the knock and, although no breaks were revealed, he will not be risked on Saturday.
Midfielder Harry Arter faces a late fitness test on a calf problem and Shaun McDonald (toe ligament damage) continues to be sidelined, but Mark Molesley will be recalled to the matchday squad.