Scunthorpe boss Ian Baraclough has a major doubt over rookie defender Ben Gordon for the crunch home clash with relegation rivals Preston.
The on-loan Chelsea left-back aggravated a hamstring injury during Saturday’s 3-0 home defeat at the hands of Leicester and was replaced at half-time by Eddie Nolan.
Midfielder Sam Togwell missed out altogether against the Foxes with a hamstring problem and will be assessed.
Fellow midfielder Michael O’Connor has been sidelined since January with a knee problem but returned to training last week and may come into contention after missing out at the weekend.
Goalkeeper Joe Murphy (ankle), midfielder Garry Thompson (groin), and right-back Cliff Byrne (back) could remain sidelined as the Iron bid to bounce back from Saturday’s defeat.
North End boss Phil Brown could be boosted by the return of Barry Nicholson, Iain Turner and David Gray for the relegation six-pointer.
The trio missed last week’s home defeat to Leeds through injury, but all look set to be passed fit to face Ian Baraclough’s men.
Turner, whose loan from Everton was extended to April 10 over the weekend, was back in training towards the end of last week after a hip problem.
Defender Callum Davidson left Deepdale by mutual consent last week and North End head to Glanford Park aiming to record their first win since Brown took the helm in January.
Brown said: “We have a points total to aim for and that is still achievable.”