Sunderland lost the first game of their pre-season tour of the United States, going down 1-0 to the United Soccer League side Sacramento Republic, who were only founded three years ago while Newcastle manager Steve McClaren suffered defeat for first time as they went down to Mexican Club Atlas.
Steven Fletcher went close before half-time for the Black Cats but his 10-yard header hit the crossbar and Ken Iwasa won the game for the home side with his second-half goal.
Sunderland boss Dick Advocaat started the game with Jack Rodwell and Adam Matthews and made four substitutions at half-time but his side were forced to settle for second best against a team managed by former Cheltenham Town and Torquay United boss Paul Buckle.
Jermain Defoe and Seb Larsson also went close for Sunderland before Duncan Watmore replaced Defoe and went close himself shortly after.
Watmore had another good opening in the closing stages but saw his left-footed effort well saved by the goalkeeper.
Sunderland are next in action on Friday when they tackle Mexican club Pachuca.
Gonzalo Ruben Bergessio scored twice in a 2-1 win for Club Atlas against Newcastle in Milwaukee.
Moussa Sissoko pulled a goal back on the stroke of half-time and then Papiss Cisse thought he had levelled for Newcastle, but the ball did not cross the line.
Newcastle travel to Sacramento to for the next leg of their tour on Saturday followed by a meeting with the Portland Timbers on Tuesday.
In other friendlies, Premier League newcomers Bournemouth beat Philadelphia Union 4-1 with Joshua King, Callum Wilson, Marc Pugh and Tokelo Rantie on target for the Cherries at PPL Park.
Norwich stormed to a 10-0 victory over Hitchin Town with Frenchman Tony Andreu scoring a hat-trick at Top Field.
In the battle of the Canaries, the Premier League outfit fielded two completely different XIs in each half.
Cameron Jerome and Gary O’Neill both bagged a brace, while West Hoolahan, Steven Whittaker and Gary Hooper also found the back of the net for Alex Neil’s side.
City have now scored a combined 17 goals in two friendly matches after, having beaten Gorleston 7-0 last weekend.