Saido Berahino is set to feature for West Brom despite speculation linking him with Tottenham, but Albion missed the deadline to sign Federico Fazio from Spurs in time for him to face the champions.
Chelsea, meanwhile, could hand debuts to Pedro and Baba Rahman.
Thibaut Courtois will hope to return between the sticks for the Blues in place of Asmir Begovic after serving a one-match suspension, while captain John Terry is likely to start in defence despite being substituted at half-time in last week’s defeat at Manchester City.
Victor Moses and Oscar miss out with undisclosed injuries.
Kick-off at The Hawthorns on Sunday is at 1.30pm.
West Brom beat Chelsea 3-0 at home last season; it was the joint-heaviest defeat that Jose Mourinho has ever suffered in the Premier League.
However, no team has beaten West Brom more often in the Premier League than Chelsea (13 wins, level with Arsenal).
Jose Mourinho’s last six Premier League defeats have come against a manager who has a surname starting in P (Pulis, Poyet, Pardew, Pochettino, Pulis, Pellegrini).
Tony Pulis has won two Premier League games against Jose Mourinho – no manager has won three PL games against the Portuguese.
Both Roberto Di Matteo and Andre Villas-Boas managed their last Premier League game as Chelsea boss against WBA at The Hawthorns before they were sacked.
No team has won the top-flight title after gaining exactly one point from their opening two games since Liverpool in 1981-82.
Chelsea have only ever lost back-to-back Premier League games under Mourinho once before; this coming in May 2006 (when Chelsea had already won the title).
Chelsea have allowed their opponents a league-high 18 shots on target so far in the 2015-16 Premier League.
The Baggies have had more possession than their opponent in just one of their last 19 Premier League matches and have the lowest average so far in 2015-16 (33.1%).
Seventeen of Saido Berahino’s 20 competitive goals for West Brom in 2014-15 came at The Hawthorns (85%), including two in a 3-0 PL win over Chelsea in May.
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